#ppiupsetalertrecord: 37-52 (41.6%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:30 PM | BTN | Penn State | #19 Michigan State | -3 | -6 | Michigan State -3 |
| 7 PM | ESPN+ | Ball State | Northern Illinois | 8.5 | 8 | |
| 7 PM | ESPN | #9 Duke | Wake Forest | 10.5 | 8 | |
| 7 PM | ESPN2 | Oklahoma | #20 Texas | -1.5 | 2 | #ppiupsetalert, Oklahoma -104 |
| 7 PM | ACCNX | Florida State | Clemson | 2 | 6 | Florida State -2 |
| 7 PM | ESPNU | Ole Miss | South Carolina | 3.5 | 1 | |
| 7 PM | SECN | Texas A&M | Florida | 1 | -2 | |
| 8 PM | CBSSN | #8 Providence | #10 Villanova | -4 | 1 | #ppiupsetalert, Providence +152 |
| 8 PM | ACCN | Georgia Tech | NC State | 2 | 3 | |
| 8:30 PM | BTN | #18 Ohio State | Minnesota | 12 | 10 | |
| 9 PM | ESPN | #16 Tennessee | #4 Kentucky | 1 | 2 | #ppiupsetalert, Tennessee -118 |
| 9 PM | ESPN2 | Indiana | #15 Wisconsin | 3.5 | -2 | #ppiupsetalert, Indiana -172 |
| 9 PM | New Mexico | #22 Wyoming | -5.5 | -9 | Wyoming -5.5 | |
| 9 PM | SECN | Missouri | #23 Arkansas | -7.5 | -5 | |
| 9 PM | Oregon State | Colorado | -4 | -9 | Colorado -4 | |
| 9 PM | FS1 | DePaul | Butler | 3.5 | 6 | |
| 9 PM | ESPNU | TCU | Iowa State | 4 | 6 | |
| 10 PM | CBSSN | San Diego State | Utah State | 3.5 | 6 | |
| 11 PM | FS1 | Nevada | San Jose State | 15 | 12 |