#ppiupsetalertrecord 65-44 (59.6%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12 PM | FOX | #20 Connecticut | Seton Hall | 9.5 | 8 | |
| 12 PM | ESPN2 | #7 Virginia | Notre Dame | 12.5 | 21 | Virginia -12.5 |
| 12 PM | ESPN | #14 Indiana | Illinois | 5.5 | 5 | |
| 1 PM | CBS | Kentucky | #10 Tennessee | -1.5 | -1 | #ppiupsetalert, Kentucky +105 |
| 2 PM | ESPN+ | #6 Texas | Oklahoma | 10.5 | 10 | |
| 2 PM | ESPN | #12 Kansas State | #19 Iowa State | 2.5 | 5 | |
| 2 PM | ACCNX | #15 Miami (FL) | Wake Forest | 6.5 | 11 | Miami (FL) -6.5 |
| 2 PM | ESPN+ | #22 TCU | Oklahoma State | 4.5 | 1 | #ppiupsetalert, Oklahoma State +172 |
| 4 PM | ESPN | #5 Kansas | #9 Baylor | 4.5 | 5 | |
| 4 PM | CBSSN | #16 Xavier | DePaul | 13.5 | 12 | |
| 4:30 PM | FOX | #24 Providence | Villanova | 4.5 | 9 | Providence -4.5 |
| 6 PM | SECN | #1 Alabama | Georgia | 18.5 | 19 | |
| 7 PM | Pepperdine | #13 Gonzaga | -16.5 | -17 | ||
| 7:30 PM | FS1 | St. John’s | #18 Creighton | -7.5 | -4 | #ppiupsetalert, St. John’s +245 |
| 8 PM | ESPN2 | #8 Arizona | Colorado | 11.5 | 14 | |
| 10 PM | ESPN2 | #17 Saint Mary’s | BYU | 9.5 | 17 | Saint Mary’s -9.5 |
| 10:30 PM | PAC12 | #4 UCLA | California | 24.5 | 32 | UCLA -24.5 |
| 12 PM | ESPNU | West Virginia | Texas Tech | 6.5 | 7 | |
| 12 PM | ACCNX | Florida State | Boston College | 1.5 | 1 | |
| 12 PM | BTN | Wisconsin | Rutgers | 0.5 | 7 | Wisconsin -0.5 |
| 1 PM | SECN | LSU | South Carolina | 6.5 | 8 | |
| 2 PM | ESPN2 | Arkansas | Florida | 8.5 | 10 | |
| 2:30 PM | ESPN3 | Western Michigan | Ball State | -8.5 | -9 | |
| 3:30 PM | SECN | Ole Miss | Mississippi State | -4.5 | -3 | |
| 5 PM | ACCN | Virginia Tech | Pittsburgh | 5.5 | -1 | Pittsburgh +172 |
| 5 PM | Fresno State | Colorado State | 0.5 | 0 | ||
| 6 PM | PAC12 | Arizona State | Utah | 2.5 | 10 | Arizona State -2.5 |
| 6 PM | ESPN | Syracuse | Duke | -1.5 | 0 | |
| 6 PM | ESPN2 | Missouri | Texas A&M | 1.5 | 0 | |
| 7 PM | ACCN | Louisville | Clemson | -10.5 | -14 | Clemson -10.5 |
| 8 PM | PAC12 | Washington | Oregon State | 8.5 | 10 | |
| 8 PM | FOX | Michigan | Michigan State | 1.5 | 1 | |
| 8 PM | CBSSN | Utah State | Nevada | 4.5 | 3 | |
| 8:30 PM | SECN | Vanderbilt | Auburn | -3.5 | -4 | |
| 9 PM | BTN | Minnesota | Penn State | -8.5 | -6 | |
| 9 PM | ESPN+ | Montana State | Montana | 5.5 | 9 | Montana State -5.5 |
| 10 PM | ESPNU | USC | Stanford | 5.5 | 10 | USC -5.5 |
| 12 PM | CBSSN | Chattanooga | UNC Greensboro | -2.5 | -2 | |
| 12 PM | Northeastern | William & Mary | 6.5 | 6 | ||
| 12:30 PM | USA Net | Davidson | Saint Joseph’s | 4.5 | 10 | Davidson -4.5 |
| 1 PM | ESPN+ | Boston University | Bucknell | 4.5 | 6 | |
| 1 PM | ESPN3 | New Hampshire | UMBC | 0.5 | 0 | |
| 1 PM | ESPN3 | UMass Lowell | Binghamton | 11.5 | 13 | |
| 1 PM | ESPN+ | VMI | Samford | -12.5 | -13 | |
| 1 PM | ESPN+ | The Citadel | Wofford | -3.5 | -3 | |
| 1 PM | Long Island | St. Francis (PA) | -6.5 | -5 | ||
| 1 PM | ESPN+ | Southern Miss | Georgia Southern | 7.5 | 15 | Southern Miss -7.5 |
| 2 PM | ESPN+ | Colgate | Holy Cross | 17.5 | 19 | |
| 2 PM | ESPN+ | American University | Lehigh | 4.5 | 3 | |
| 2 PM | ESPN3 | Indiana State | Illinois State | 13.5 | 15 | |
| 2 PM | ESPN3 | Maine | Albany | 8.5 | 11 | |
| 2 PM | ESPNU | Rhode Island | Massachusetts | 4.5 | 5 | |
| 2 PM | ESPN+ | Campbell | Presbyterian College | 7.5 | 13 | Campbell -7.5 |
| 2 PM | ESPN+ | Mercer | Western Carolina | 4.5 | 4 | |
| 2 PM | ESPN3 | Central Michigan | Ohio | -7.5 | -6 | |
| 2 PM | ESPN+ | Coastal Carolina | Texas State | -1.5 | 3 | Coastal Carolina -102 |
| 2 PM | ESPN+ | Youngstown State | Green Bay | 22.5 | 29 | Youngstown State -22.5 |
| 2 PM | Monmouth | Elon | -1.5 | 6 | Monmouth -110 | |
| 2 PM | ESPN+ | Kennesaw State | Queens University | 8.5 | 13 | Kennesaw State -8.5 |
| 2:30 PM | USA Net | VCU | Fordham | 7.5 | 5 | |
| 3 PM | ESPN+ | Louisiana Tech | Charlotte | 1.5 | 0 | |
| 3 PM | ESPN+ | Stephen F. Austin | UT-Arlington | 11.5 | 12 | |
| 3 PM | ESPN+ | Longwood | Radford | 4.5 | 1 | Radford +4.5 |
| 3 PM | ESPN+ | UNC Asheville | Gardner-Webb | 1.5 | 7 | UNC Asheville -1.5 |
| 3 PM | ESPN+ | Arkansas State | Georgia State | 0.5 | 0 | |
| 3 PM | Denver | South Dakota | 3.5 | 2 | ||
| 3 PM | ESPN+ | Morehead State | Lindenwood | 9.5 | 14 | Morehead State -9.5 |
| 3 PM | ESPN+ | Idaho | Northern Arizona | 2.5 | 5 | |
| 4 PM | Coppin State | Howard | -6.5 | -7 | ||
| 4 PM | Maryland-Eastern Shore | South Carolina State | 8.5 | 12 | Maryland-Eastern Shore -8.5 | |
| 4 PM | ESPN2 | Grambling State (N) | Southern University (N) | 2.5 | 4 | |
| 4 PM | Jackson State | Alcorn State | 1.5 | -1 | ||
| 4 PM | Delaware State | North Carolina Central | -8.5 | -5 | Delaware State +8.5 | |
| 4 PM | ESPN3 | Missouri State | Northern Iowa | 5.5 | 7 | |
| 4 PM | ESPN3 | Murray State | Evansville | 11.5 | 19 | Murray State -11.5 |
| 4 PM | ESPN+ | Navy | Loyola (MD) | 10.5 | 13 | |
| 4 PM | UTSA | UAB | -15.5 | -12 | UTSA +15.5 | |
| 4 PM | Norfolk State | Morgan State | 12.5 | 12 | ||
| 4 PM | ESPN3 | Nicholls State | Incarnate Word | 10.5 | 13 | |
| 4 PM | ESPN+ | George Mason | La Salle | 5.5 | 7 | |
| 4 PM | ESPN3 | High Point | South Carolina State | 1.5 | 6 | High Point -1.5 |
| 4 PM | Wagner | Fairleigh Dickinson | 2.5 | 5 | ||
| 4 PM | ESPN+ | South Alabama | UL Monroe | 11.5 | 7 | UL Monroe +11.5 |
| 4 PM | ESPN+ | Appalachian State | Old Dominion | 2.5 | 2 | |
| 4 PM | ESPN+ | Tennessee Tech | Tennessee-Martin | 1.5 | 1 | |
| 4 PM | Delaware | UNC Wilmington | 1.5 | -7 | UNC Wilmington +1.5 | |
| 4 PM | Towson | North Carolina A&T | 12.5 | 11 | ||
| 4 PM | Hampton | Drexel | -4.5 | -7 | ||
| 4 PM | ESPN+ | UC Irvine | UC Davis | 7.5 | 10 | |
| 4 PM | ESPN+ | Austin Peay | North Florida | -2.5 | -5 | |
| 4:30 PM | ESPN3 | Northwestern State | New Orleans | 12.5 | 18 | Northwestern State -12.5 |
| 4:30 PM | ESPN3 | McNeese State | Texas A&M-Corpus Christi | -4.5 | -6 | |
| 4:30 PM | ESPN3 | Northern Illinois | Miami (OH) | 5.5 | 7 | |
| 4:30 PM | ESPN+ | Tennessee State | SIU-Edwardsville | 1.5 | 0 | |
| 4:30 PM | ESPN+ | Little Rock | Eastern Illinois | 4.5 | 5 | |
| 5 PM | ESPN3 | Bowling Green | Toledo | -8.5 | -12 | Toledo -8.5 |
| 5 PM | ESPN+ | Southeast Missouri State | Southern Indiana | 3.5 | 1 | |
| 5 PM | ESPN+ | Eastern Washington | Northern Colorado | 8.5 | 13 | Eastern Washington -8.5 |
| 5:30 PM | ESPN+ | Charleston Southern | Winthrop | -2.5 | -1 | |
| 6 PM | Texas Southern | Mississippi Valley State | 10.5 | 10 | ||
| 6 PM | CBSSN | Army | Lafayette | 3.5 | 6 | |
| 6 PM | ESPN+ | Middle Tennessee | Florida International | 7.5 | 10 | |
| 6 PM | ESPN+ | Jacksonville State | Liberty | -9.5 | -7 | |
| 6 PM | ESPN+ | Florida Gulf Coast | Stetson | 4.5 | 4 | |
| 6:30 PM | Alabama State | Florida A&M | 6.5 | 6 | ||
| 6:30 PM | Stony Brook | Hofstra | -12.5 | -12 | ||
| 7 PM | ESPN3 | NJIT | Vermont | -11.5 | -10 | |
| 7 PM | ESPN3 | Columbia | Dartmouth | -3.5 | -2 | |
| 7 PM | ESPN3 | Akron | Buffalo | 9.5 | 9 | |
| 7 PM | ESPN+ | Marshall | Troy | 8.5 | 11 | |
| 7 PM | ESPN+ | James Madison | Louisiana Lafayette | 2.5 | 1 | |
| 7 PM | ESPN+ | Robert Morris | Milwaukee | 3.5 | -1 | Milwaukee +134 |
| 7 PM | ESPN+ | Cal State Fullerton | Cal Poly | 10.5 | 14 | Cal State Fullerton -10.5 |
| 7 PM | ESPN+ | Long Beach State | Hawaii | 2.5 | 3 | |
| 7 PM | ESPN+ | Sacramento State | Idaho State | 4.5 | 6 | |
| 7 PM | ESPN+ | Eastern Kentucky | North Alabama | 7.5 | 7 | |
| 8 PM | ESPNU | South Florida | Tulane | -2.5 | -5 | |
| 8 PM | ESPN+ | Rice | Western Kentucky | 1.5 | 8 | Rice -1.5 |
| 8 PM | ESPN+ | Houston Christian | Lamar | 3.5 | 2 | |
| 8 PM | ESPN+ | Saint Louis | Duquesne | 4.5 | 5 | |
| 8 PM | ESPN+ | Tarleton State | Sam Houston State | -2.5 | -3 | |
| 8 PM | ESPN+ | Seattle | Utah Valley | -2.5 | 0 | |
| 8 PM | St. Thomas-Minnesota | Western Illinois | 7.5 | 6 | ||
| 8 PM | Oral Roberts | North Dakota State | 13.5 | 5 | North Dakota State +13.5 | |
| 8 PM | Kansas City | North Dakota | 2.5 | 6 | Kansas City -2.5 | |
| 8 PM | Omaha | South Dakota State | -5.5 | -7 | ||
| 8 PM | ESPN+ | UC Riverside | UC Santa Barbara | -1.5 | 5 | UC Riverside +112 |
| 8:30 PM | Portland | Santa Clara | -2.5 | -5 | ||
| 9 PM | ESPN+ | UTEP | North Texas | -5.5 | -8 | |
| 10 PM | Loyola Marymount | Pacific | 9.5 | 13 | Loyola Marymount -9.5 | |
| 10 PM | ESPN+ | UC San Diego | CS Northridge | 5.5 | 9 | UC San Diego -5.5 |
| 10 PM | ESPN+ | Portland State | Weber State | 0.5 | -1 |