#ppiposseofpicks: 151-177 (.460)
#ppiupsetalert: 45-57 (.441)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | ESPN | #1 Baylor | #3 Kansas | 2.5 | 3 | #ppiupsetalert, Kansas +104 |
| 12 PM | CBS | #13 Auburn | Tennessee | 6.5 | 10 | Auburn -6.5 |
| 12 PM | FOX | Providence | #19 Marquette | 2 | 2 | #ppiupsetalert, Providence -136 |
| 2 PM | #5 Dayton | Duquesne | 14 | 16 | ||
| 2 PM | ESPNU | TCU | #17 West Virginia | -5 | -4 | #ppiupsetalert, TCU +5 |
| 2 PM | ESPN2 | Memphis | #22 Houston | -2.5 | -3 | #ppiupsetalert, Memphis +120 |
| 2:30 PM | FOX | Xavier | #12 Villanova | 0 | -1 | #ppiupsetalert, Xavier -110 |
| 4 PM | ACCN | NC State | #8 Florida State | -1 | -2 | #ppiupsetalert, NC State +102 |
| 4 PM | ESPN | #11 Louisville | North Carolina | 9 | 18 | Louisville -9 |
| 4 PM | CBS | #18 Colorado | UCLA | 10.5 | 13 | |
| 6 PM | ESPN | #10 Kentucky | Florida | 5 | 9 | Kentucky -5 |
| 7:30 PM | CBSSN | #4 San Diego State | UNLV | 14.5 | 18 | |
| 8 PM | ESPN2 | #6 Duke | Virginia Tech | 16.5 | 17 | |
| 9 PM | ESPN | #24 Arizona | #14 Oregon | 5 | 4 | #ppiupsetalert, Arizona -200 |
| 10 PM | ESPN2 | #23 BYU | #2 Gonzaga | -4.5 | -3 | #ppiupsetalert, BYU +140 |
| 4 PM | ESPN+ | Fordham | Massachusetts | -1.5 | -2 | |
| 4 PM | ESPN+ | George Washington | La Salle | 3 | 3 | |
| 4:30 PM | George Mason | Saint Joseph’s | 9 | 12 | ||
| 5:30 PM | CBSSN | Davidson | Rhode Island | 2.5 | -2 | Rhode Island +120 |
| 6:30 PM | St. Bonaventure | Richmond | -1.5 | -2 | ||
| 12 PM | ESPN2 | Pittsburgh | Virginia | -3 | -2 | |
| 4 PM | ACCNX | Syracuse | Georgia Tech | 5 | 4 | |
| 6 PM | ACCN | Boston College | Clemson | -4 | 1 | Boston College +160 |
| 12 PM | ESPNU | UCF | Tulane | 7.5 | 11 | |
| 3 PM | ESPNN | Tulsa | SMU | 1.5 | 3 | |
| 2 PM | CBS | Kansas State | Texas | 4.5 | -2 | Texas +170 |
| 4 PM | ESPN2 | Oklahoma State | Oklahoma | -1 | 1 | |
| 6 PM | ESPNU | Iowa State | Texas Tech | -6 | -1 | Iowa State +195 |
| 9 PM | FS1 | DePaul | Georgetown | 2.5 | -1 | Georgetown +110 |
| 9 PM | Montana State | Montana | -3.5 | -1 | ||
| 2 PM | ESPN | Purdue | Michigan | 2.5 | 2 | |
| 1 PM | ESPN3 | Ball State | Eastern Michigan | 6 | 5 | |
| 6 PM | PAC12 | Washington | California | 9.5 | 4 | California +9.5 |
| 8 PM | ESPNU | Arizona State | Oregon State | 6 | 11 | Arizona State -6 |
| 1 PM | SECN | Arkansas | Missouri | 6.5 | 7 | |
| 3:30 PM | SECN | Texas A&M | Mississippi State | -4.5 | -2 | |
| 6 PM | SECN | Vanderbilt | Georgia | -2.5 | 0 | #closegamealert |
| 6 PM | ESPN2 | South Carolina | LSU | -1 | 0 | #closegamealert |
| 8:30 PM | SECN | Ole Miss | Alabama | 2.5 | 0 | #closegamealert |