#ppiposseofpicks: 164-188 (.466)
#ppiupsetalert: 52-62 (.456)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | George Mason | #4 Dayton | -12 | -11 | ||
| 7 PM | ACCN | Wake Forest | #7 Duke | -10.5 | -10 | |
| 7 PM | ESPN | Texas A&M | #8 Kentucky | -6.5 | -6 | |
| 7 PM | SECN | #15 Auburn | Ole Miss | 9 | 13 | Auburn -9 |
| 7 PM | ESPN2 | #24 Michigan State | #18 Iowa | 7.5 | 5 | #ppiupsetalert, Michigan State -340 |
| 8 PM | ESPN+ | #2 Baylor | Kansas State | 14 | 22 | Baylor -14 |
| 9 PM | ESPN2 | Oklahoma | #22 Texas Tech | -3 | 2 | #ppiupsetalert, Oklahoma +130, #OklaBubble |
| 11 PM | CBSSN | #5 San Diego State | Colorado State | 14 | 13 | |
| 7 PM | ESPN+ | Davidson | La Salle | 11.5 | 7 | LaSalle +11.5 |
| 9 PM | ESPN | North Carolina | NC State | 2.5 | -2 | NC State +125, NCStateBubble |
| 9 PM | ACCN | Georgia Tech | Clemson | 2.5 | 3 | #ClemsonbBubble |
| 9 PM | CBSSN | SMU | Memphis | 4 | 3 | #MemphisBubble |
| 9 PM | ESPNU | Tulsa | Tulane | 11 | 12 | #TulsaBubble |
| 7 PM | ESPNU | Iowa State | TCU | 3 | 2 | |
| 7 PM | CBSSN | Xavier | DePaul | 8 | 9 | |
| 7 PM | ESPN+ | Ball State | Western Michigan | 10.5 | 10 | |
| 9 PM | SECN | Mississippi State | Alabama | 3.5 | 3 | #MissStBubble #AlabamaBubble #DoubleBubble |