#ppiupsetalert record: 42-41 (.506)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | CBSSN | #1 Gonzaga | Santa Clara | 31 | 26 | Santa Clara +26 |
| 7 PM | ESPN | #3 Michigan | #9 Iowa | 5 | 5 | #ppiupsetalert, Iowa +5 |
| 7 PM | BTN | #5 Illinois | Nebraska | 14.5 | 21 | Illinois -14.5 |
| 7 PM | #12 Houston | Western Kentucky | 11.5 | 12 | #WesternKYBubble | |
| 9 PM | ESPN | Michigan State | #4 Ohio State | -4 | -6 | #MichiganStBubble |
| 9 PM | Colorado | #19 USC | 2.5 | 0 | #ppiupsetalert, Colorado -153 | |
| 9 PM | FS1 | #22 San Diego State | Boise State | 6.5 | 5 | |
| 7 PM | FS1 | Arizona State | Washington | 9.5 | 9 | |
| 8 PM | PAC12 | Utah | UCLA | -1 | -3 | |
| 8 PM | ESPN+ | Eastern Kentucky | Belmont | -8 | -6 | #BelmontBubble |
| 9 PM | CBSSN | BYU | San Francisco | 10 | 11 | |
| 9 PM | Stanford | Oregon | 1 | 4 | #OregonBubble, Stanford -1 | |
| 9 PM | BTN | Minnesota | Northwestern | 4.5 | 11 | #MinnesotaBubble, Minnesota -4.5 |
| 11 PM | Saint Mary’s | Pacific | 7 | 9 | #SaintMary’sBubble | |
| 11 PM | FS1 | Arizona | Washington State | 9 | 6 | Washington State +9 |