#ppiposseofpicks: 121-155 (.438)
#ppiupsetalert: 34-45 (.430)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | ESPN | Boston College | #7 Duke | -14.5 | -9 | Boston College +14.5 |
| 7 PM | FS1 | #9 Maryland | Rutgers | 7.5 | 10 | |
| 7 PM | SECN | Arkansas | #11 Auburn | 1 | 2 | |
| 8 PM | BTN | #16 Michigan State | #22 Penn State | 8.5 | 7 | |
| 9 PM | ESPN | #15 Kentucky | Mississippi State | 6.5 | 6 | |
| 7 PM | CBSSN | Rhode Island | Massachusetts | 16 | 16 | |
| 7 PM | ACCN | Georgia Tech | Virginia Tech | 2 | 3 | |
| 9 PM | ESPN2 | Texas Tech | Oklahoma | 9 | 1 | Oklahoma +9 |
| 9 PM | FS1 | DePaul | Xavier | 1 | 0 | |
| 7 PM | ESPN2 | Michigan | Ohio State | 2.5 | 3 | |
| 7 PM | ESPN+ | Kent State | Ball State | 3.5 | 6 | |
| 7 PM | ESPNU | Alabama | Tennessee | 5.5 | 9 | |
| 9 PM | SECN | Texas A&M | Missouri | 1 | 3 |