#ppiupsetalertrecord 52-36 (59.1%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12 PM | FS1 | Georgetown | #24 Connecticut | -14 | -15 | |
| 12 PM | ESPN2 | Virginia Tech | #6 Virginia | 1.5 | -6 | Virginia -102 |
| 12 PM | ESPN | #13 Iowa State | #8 Kansas | -1.5 | -2 | #ppiupsetalert, Iowa State +108 |
| 1 PM | CBS | #11 Baylor | Texas Tech | 9.5 | 11 | |
| 2 PM | ESPN | #2 Tennessee | #25 Auburn | 9.5 | 4 | Auburn +9.5 |
| 2 PM | FS1 | #14 Marquette | Butler | 15.5 | 15 | |
| 2 PM | ESPN+ | Oklahoma State | #15 TCU | 3.5 | 8 | #ppiupsetalert, Oklahoma State -182 |
| 3 PM | ACCN | #20 Clemson | #23 Miami (FL) | 1.5 | 0 | #ppiupsetalert, Miami (FL) +112 |
| 4 PM | ESPN | #21 Indiana | #1 Purdue | 1.5 | -10 | Purdue +100 |
| 4 PM | ESPNU | LSU | #4 Alabama | -11.5 | -11 | |
| 4 PM | ESPN2 | #7 Kansas State | #10 Texas | -1.5 | 4 | #ppiupsetalert, Texas -111 |
| 4 PM | ESPN+ | Charlotte | #19 Florida Atlantic | -5.5 | -7 | |
| 5 PM | FOX | #16 Xavier | St. John’s | 7.5 | 8 | |
| 7 PM | PAC12 | #9 UCLA | Washington State | 11.5 | 20 | UCLA -11.5 |
| 9:30 PM | PAC12 | #5 Arizona | Oregon State | 20.5 | 22 | |
| 10:30 PM | ESPN | #18 Saint Mary’s | #12 Gonzaga | 2.5 | 5 | #ppiupsetalert, Saint Mary’s -156 |
| 6 PM | ESPN+ | Montana State | Northern Colorado | 11.5 | 13 | |
| 12 PM | FOX | Rutgers | Michigan State | 4.5 | 2 | |
| 1 PM | ACCNX | Notre Dame | Wake Forest | -3.5 | -5 | |
| 1 PM | ACCN | NC State | Georgia Tech | 15.5 | 18 | |
| 1 PM | SECN | Vanderbilt | Ole Miss | 3.5 | 5 | |
| 2 PM | ESPN2 | Louisville | Florida State | -5.5 | -2 | Louisville +5.5 |
| 2:30 PM | FOX | Iowa | Illinois | 1.5 | 1 | |
| 3:30 PM | SECN | South Carolina | Arkansas | -12.5 | -10 | |
| 5 PM | ACCN | Boston College | Syracuse | -3.5 | -1 | |
| 6 PM | SECN | Mississippi State | Missouri | 3.5 | 1 | |
| 6:30 PM | ESPN | Duke | North Carolina | 2.5 | 5 | |
| 7:30 PM | FOX | Creighton | Villanova | 10.5 | 10 | |
| 8 PM | ESPNN | West Virginia | Oklahoma | 5.5 | 6 | |
| 8 PM | CBSSN | Colorado State | Utah State | -5.5 | -7 | |
| 8:30 PM | SECN | Texas A&M | Georgia | 11.5 | 11 | |
| 8:30 PM | ESPN | Kentucky | Florida | 4.5 | 7 | |
| 9 PM | BTN | Minnesota | Maryland | -9.5 | -9 | |
| 9:30 PM | FS1 | USC | Washington | 9.5 | 10 | |
| 10 PM | ESPN2 | Arizona State | Oregon | 0.5 | 4 | Arizona State -0.5 |
| 10 PM | CBSSN | San Jose State | Wyoming | 0.5 | 12 | San Jose -0.5 |
| 12 PM | ESPNU | Cincinnati | UCF | 6.5 | 5 | |
| 12 PM | ESPN+ | SE Louisiana | Texas A&M-Corpus Christi | -1.5 | 6 | SE Louisiana +102 |
| 12 PM | ESPN+ | IUPUI | Green Bay | 3.5 | 5 | |
| 12:30 PM | USA | Massachusetts | Davidson | -1.5 | 2 | Massachusetts -102 |
| 1 PM | ESPN+ | Lafayette | Lehigh | 1.5 | -3 | |
| 1 PM | ESPN3 | UMass Lowell | NJIT | 12.5 | 17 | UMass Lowell -12.5 |
| 1 PM | ESPN3 | Bryant University | New Hampshire | 6.5 | 7 | |
| 1 PM | Morgan State (N) | Delaware State (N) | 3.5 | 5 | ||
| 1 PM | ESPN+ | The Citadel | UNC Greensboro | -9.5 | -9 | |
| 1 PM | Fairleigh Dickinson | Wagner | 3.5 | 4 | ||
| 1 PM | St. Francis (BKN) | Stonehill | 1.5 | 4 | ||
| 1 PM | ESPN+ | Oakland | Cleveland State | -1.5 | 0 | |
| 1 PM | ESPN+ | Detroit Mercy | Purdue Fort Wayne | 1.5 | 0 | |
| 2 PM | Hartford | Chicago State | -7 | -4 | Hartford +7 | |
| 2 PM | ESPNU | Memphis | Tulane | 6.5 | 6 | |
| 2 PM | ESPN+ | UIC | Evansville | 8.5 | 12 | UIC -8.5 |
| 2 PM | ESPN3 | Maine | UMBC | -4.5 | -2 | |
| 2 PM | ESPN3 | Holy Cross | Navy | -5.5 | -3 | |
| 2 PM | ESPN+ | George Washington | Duquesne | 0.5 | 0 | |
| 2 PM | ESPN+ | Radford | Winthrop | 6.5 | 10 | Radford -6.5 |
| 2 PM | ESPN+ | Gardner-Webb | Presbyterian College | 11.5 | 16 | Gardner-Webb -11.5 |
| 2 PM | ESPN+ | Longwood | Campbell | 8.5 | 6 | |
| 2 PM | ESPN+ | Western Carolina | Chattanooga | 1.5 | 0 | |
| 2 PM | ESPN+ | Mercer | VMI | 9.5 | 12 | |
| 2 PM | ESPN3 | Ohio | Miami (OH) | 9.5 | 14 | Ohio -9.5 |
| 2 PM | Sacred Heart | Central Connecticut State | 0 | 10 | ||
| 2 PM | ESPN+ | Georgia State | Southern Miss | -3.5 | -9 | Southern Miss -3.5 |
| 2 PM | South Dakota | North Dakota | 5.5 | 10 | South Dakota -5.5 | |
| 2 PM | William & Mary | UNC Wilmington | -6.5 | -9 | ||
| 2 PM | Delaware | Charleston | -7.5 | -10 | ||
| 2 PM | Northeastern | Elon | 6.5 | 12 | Northeastern -6.5 | |
| 2 PM | Monmouth | Drexel | -6.5 | -4 | ||
| 2 PM | ESPN+ | Stetson | Central Arkansas | 9.5 | 13 | Stetson -9.5 |
| 2:30 PM | USA Net | Loyola (CHI) | George Mason | -1.5 | -3 | |
| 2:30 PM | ESPN3 | Western Michigan | Buffalo | -3.5 | -5 | |
| 3 PM | ESPN+ | Albany | Vermont | -12.5 | -12 | |
| 3 PM | ESPN+ | Samford | East Tennessee State | 9.5 | 12 | |
| 3 PM | Merrimack | St. Francis (PA) | 4.5 | 3 | ||
| 3 PM | ESPN+ | UL Monroe | South Alabama | -2.5 | 5 | UL Monroe +132 |
| 3 PM | ESPN+ | Arkansas State | Coastal Carolina | -2.5 | -2 | |
| 3 PM | ESPN3 | South Dakota State | North Dakota State | 6.5 | 10 | South Dakota State -6.5 |
| 3 PM | Omaha | Western Illinois | -1.5 | -1 | ||
| 4 PM | ESPN+ | East Carolina | SMU | -2.5 | 1 | East Carolina +110 |
| 4 PM | ESPN+ | American University | Colgate | -5.5 | -3 | |
| 4 PM | ESPN3 | Indiana State | Murray State | 6.5 | 3 | Murray State +6.5 |
| 4 PM | Western Kentucky | UTEP | 2.5 | 2 | ||
| 4 PM | ESPN+ | UAB | Florida International | 14.5 | 11 | Florida International +14.5 |
| 4 PM | TNT | Hampton (N) | Norfolk State (N) | -8.5 | -13 | Norfolk State -8.5 |
| 4 PM | ESPN+ | South Carolina Upstate | UNC Asheville | -4.5 | -5 | |
| 4 PM | ESPN+ | Appalachian State | James Madison | -2.5 | -1 | |
| 4 PM | ESPN+ | Tennessee Tech | Southeast Missouri State | -1.5 | 1 | |
| 4 PM | Hofstra | Stony Brook | 15.5 | 18 | ||
| 4 PM | ESPN+ | Bellarmine | Jacksonville State | 3.5 | 5 | |
| 4 PM | ESPN+ | Austin Peay | Queens University | -4.5 | -4 | |
| 4:30 PM | Alabama State | Grambling State | -5.5 | -7 | ||
| 4:30 PM | ESPN+ | Southern Indiana | Morehead State | 2.5 | 3 | |
| 4:30 PM | ESPN+ | Eastern Illinois | Tennessee State | -1.5 | -2 | |
| 4:30 PM | ESPN+ | Little Rock | SIU-Edwardsville | -4.5 | -6 | |
| 4:30 PM | ESPN+ | Lindenwood | Tennessee-Martin | -3.5 | -5 | |
| 5 PM | Alcorn State | Arkansas-Pine Bluff | 7.5 | 8 | ||
| 5 PM | ESPN+ | Loyola (MD) | Boston University | -1.5 | 0 | |
| 5 PM | ESPN3 | Belmont | Illinois State | 10.5 | 15 | Belmont -10.5 |
| 5 PM | ESPN+ | New Orleans | Incarnate Word | 3.5 | 2 | |
| 5 PM | ESPN+ | UT-Arlington | Sam Houston State | -7.5 | -10 | |
| 5 PM | ESPN+ | Tarleton State | UT-Rio Grande Valley | 9.5 | 10 | |
| 5 PM | ESPN3 | Bowling Green | Northern Illinois | 5.5 | 3 | |
| 5 PM | ESPN+ | Sacramento State | Idaho | 6.5 | 13 | Sacramento State -6.5 |
| 5 PM | ESPN+ | Lipscomb | Liberty | -8.5 | -2 | Lipscomb +8.5 |
| 5 PM | ESPN+ | North Florida | Jacksonville | 1.5 | 0 | |
| 5:30 PM | ESPN+ | Texas A&M-Commerce | McNeese State | 3.5 | 10 | Texas A&M-Commerce -3.5 |
| 6 PM | Texas Southern | Florida A&M | 13.5 | 8 | Florida A&M +13.5 | |
| 6 PM | Alabama A&M | Southern University | -5.5 | -6 | ||
| 6 PM | ESPN+ | Princeton | Columbia | 16.5 | 21 | Princeton -16.5 |
| 6 PM | ESPN+ | Northern Iowa | Bradley | -2.5 | -3 | |
| 6 PM | ESPN+ | Dartmouth | Yale | -8 | -9 | |
| 6 PM | ESPN+ | Pennsylvania | Cornell | 1.5 | 0 | |
| 6 PM | ESPN+ | Harvard | Brown | 3.5 | 4 | |
| 6 PM | ESPN+ | Middle Tennessee | UTSA | 13.5 | 18 | Middle Tennessee -13.5 |
| 6 PM | ESPN+ | Furman | Wofford | 10.5 | 12 | |
| 6 PM | Denver | St. Thomas-Minnesota | -1.5 | 1 | ||
| 6:30 PM | Jackson State | Mississippi Valley State | 9.5 | 13 | Jackson State -9.5 | |
| 6:30 PM | Prairie View A&M | Bethune-Cookman | 7.5 | 8 | ||
| 7 PM | ESPN+ | Bucknell | Army | -2.5 | -1 | |
| 7 PM | ESPN+ | Valparaiso | Drake | -8.5 | -10 | |
| 7 PM | ESPN+ | Lamar | Northwestern State | -9.5 | -10 | |
| 7 PM | ESPN+ | High Point | Charleston Southern | 1.5 | 5 | High Point -1.5 |
| 7 PM | ESPN3 | Toledo | Central Michigan | 18.5 | 20 | |
| 7 PM | ESPN+ | Old Dominion | Georgia Southern | 5.5 | 8 | |
| 7 PM | ESPN+ | Troy | Texas State | 4.5 | 7 | |
| 7 PM | ESPN+ | Youngstown State | Northern Kentucky | 3.5 | 8 | Youngstown State -3.5 |
| 7 PM | ESPN+ | Robert Morris | Wright State | 1.5 | 2 | |
| 7 PM | ESPN+ | Long Beach State | UC Irvine | 1.5 | 1 | |
| 7 PM | ESPN+ | Florida Gulf Coast | North Alabama | 8.5 | 9 | |
| 7 PM | ESPN+ | Eastern Kentucky | Kennesaw State | 1.5 | -1 | |
| 8 PM | ESPN+ | Rice | North Texas | -5.5 | -3 | |
| 8 PM | ESPN+ | Houston Christian | Nicholls State | -6.5 | -7 | |
| 8 PM | ESPN+ | St. Bonaventure | Dayton | -5.5 | 0 | St. Bonaventure +195 |
| 8 PM | ESPN+ | Grand Canyon | Stephen F. Austin | 3.5 | 4 | |
| 8 PM | Pepperdine | Portland | -1.5 | -4 | ||
| 8 PM | ESPN+ | Louisiana Lafayette | Marshall | 0.5 | 3 | |
| 8 PM | Kansas City | Oral Roberts | -8.5 | -10 | ||
| 8 PM | ESPN+ | Idaho State | Weber State | -3.5 | -1 | |
| 9 PM | ESPN+ | New Mexico State | Seattle | 2.5 | -5 | Seattle +114 |
| 9 PM | ESPN+ | Utah Tech | Southern Utah | -4.5 | -4 | |
| 9 PM | BYU | Pacific | 14.5 | 12 | ||
| 9 PM | ESPN+ | Cal State Fullerton | UC Riverside | 2.5 | -3 | UC Riverside +126 |
| 9 PM | ESPN+ | Montana | Northern Arizona | 7.5 | 9 | |
| 10 PM | ESPN+ | California Baptist | Abilene Christian | 4.5 | 7 | |
| 10 PM | ESPNU | San Francisco | Santa Clara | 2.5 | 2 | |
| 10 PM | San Diego | Loyola Marymount | -4.5 | -6 | ||
| 10 PM | ESPN+ | UC San Diego | CSU Bakersfield | 5.5 | 10 | UC San Diego -5.5 |
| 10 PM | ESPN+ | Cal Poly | Hawaii | -7.5 | -9 | |
| 10 PM | ESPN+ | CS Northridge | UC Santa Barbara | -14.5 | -10 | CS Northridge +14.5 |
| 10 PM | ESPN+ | Portland State | Eastern Washington | -4.5 | -6 |