#ppiposseofpicks: 93-110 (.458)
#ppiupsetalert: 22-26 (.458)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:30 PM | FS1 | #5 Butler | #18 Seton Hall | 5 | 6 | |
| 6:30 PM | SECN | South Carolina | #10 Kentucky | -5.5 | -8 | |
| 7 PM | ESPN2 | #9 Florida State | Virginia | 6 | 11 | Florida St -6 |
| 7 PM | CBSSN | Georgetown | #25 Creighton | 2.5 | 3 | #ppiupsetalert, Georgetown -130 |
| 8 PM | ESPN+ | #2 Baylor | Iowa State | 9.5 | 13 | |
| 9 PM | ESPN2 | Alabama | #4 Auburn | -2 | -3 | |
| 9 PM | ESPNU | Temple | #16 Wichita State | -4.5 | -5 | |
| 7 PM | ESPN+ | Duquesne | Fordham | 17 | 18 | |
| 7 PM | ESPN+ | George Washington | George Mason | -3 | -10 | George Mason -3 |
| 7 PM | ESPN+ | St. Bonaventure | Massachusetts | 8.5 | 9 | |
| 7:30 PM | ESPN+ | Saint Joseph’s | Rhode Island | -8 | -9 | |
| 6:30 PM | ACCNX | Syracuse | Boston College | 12 | 7 | Boston College +12 |
| 7 PM | ACCNX | NC State | Miami (FL) | 8 | 3 | Miami (FL) +8 |
| 8:30 PM | ACCN | Georgia Tech | Notre Dame | 2 | 5 | |
| 7 PM | ESPN3 | East Carolina | Tulsa | -2.5 | -3 | |
| 9 PM | CBSSN | Houston | SMU | 8 | 7 | |
| 8 PM | ESPN+ | Oklahoma State | Texas | 3 | 4 | |
| 8 PM | Marquette | Xavier | 3 | 2 | ||
| 8:30 PM | FS1 | Providence | St. John’s | 5 | 4 | |
| 7 PM | BTN | Rutgers | Illinois | 3.5 | 2 | |
| 9 PM | BTN | Minnesota | Penn State | 2.5 | 3 | |
| 10 PM | PAC12 | UCLA | Stanford | -1.5 | -8 | Stanford -1.5 |
| 7 PM | ESPNU | Georgia | Tennessee | 2.5 | 3 | |
| 8:30 PM | SECN | Arkansas | Vanderbilt | 14 | 17 |