#ppiupsetalert record: 8-21 (.276)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:30 PM | BTN | #15 Ohio State | Purdue | 4.5 | 4 | Purdue +4.5, #ppiupsetalert |
| 7 PM | ESPN | Florida | #6 Tennessee | -7 | -3 | Florida +7, #ppiupsetalert |
| 7 PM | FS1 | #7 Michigan | Maryland | 10.5 | 15 | Michigan -10.5 |
| 7 PM | SECN | #19 Missouri | South Carolina | 6 | 15 | Missouri -6 |
| 8:30 PM | BTN | #22 Illinois | Penn State | 9 | 16 | Illinois -9.5 |
| 9 PM | FS1 | #3 Villanova | Seton Hall | 9 | 4 | Seton Hall +9, #ppiupsetalert |
| 9 PM | ESPN2 | LSU | #18 Alabama | 1 | -4 | LSU -115 |
| 6:30 PM | Oklahoma | Kansas State | 14 | 14 | ||
| 7 PM | ESPN2 | Oregon State | USC | -10.5 | -11 | |
| 7 PM | CBSSN | DePaul | Butler | 0 | 1 | |
| 7 PM | ACCN | Syracuse | Miami (FL) | 4.5 | 7 | |
| 7 PM | ESPN3 | Miami (OH) | Ball State | -4 | -1 | |
| 9 PM | ESPN | Pittsburgh | Duke | -3.5 | 9 | Pittsburgh +3.5 |
| 9 PM | SECN | Mississippi State | Ole Miss | 3 | 10 | Mississippi State -3 |