#ppiupsetalertrecord 37-23 (61.7%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12 PM | FS1 | #8 Xavier | Georgetown | 17.5 | 23 | Xavier -17.5 |
| 12 PM | ESPN | Duke | #17 Miami (FL) | 5.5 | 1 | #ppiupsetalert, Duke -235 |
| 12 PM | Northeastern | #18 Charleston | -9.5 | -15 | Charleston -9.5 | |
| 12 PM | ESPN2 | #25 Arkansas | Ole Miss | 9.5 | 12 | |
| 1 PM | CBS | #2 Kansas | #14 TCU | 7.5 | 14 | Kansas -7.5 |
| 2 PM | ABC | #11 Arizona | #5 UCLA | 1.5 | 2 | #ppiupsetalert, Arizona -118 |
| 2 PM | ESPNU | Wake Forest | #10 Virginia | -2.5 | -1 | #ppiupsetalert, Wake Forest +128 |
| 2 PM | ESPN+ | Oklahoma State | #12 Iowa State | -1.5 | 3 | #ppiupsetalert, Oklahoma State -102 |
| 2 PM | ESPN2 | #13 Kansas State | Texas Tech | 4.5 | 13 | Kansas State -4.5 |
| 2 PM | FS1 | #22 Providence | DePaul | 9.5 | 14 | Providence -9.5 |
| 3:30 PM | SECN | South Carolina | #16 Auburn | -12.5 | -14 | |
| 4 PM | ESPN | LSU | #9 Tennessee | -11.5 | -4 | #ppiupsetalert, LSU +460 |
| 4 PM | CBSSN | Seton Hall | #20 Marquette | -1.5 | 0 | #ppiupsetalert, Seton Hall +104 |
| 4 PM | ESPN2 | Oklahoma | #21 Baylor | -1.5 | 2 | #ppiupsetalert., Oklahoma +112 |
| 6 PM | SECN | Missouri | #4 Alabama | -5.5 | -8 | |
| 6 PM | ESPN | West Virginia | #7 Texas | 0.5 | 1 | #ppiupsetalert, West Virginia -110 |
| 6 PM | ESPN2 | #19 Clemson | Virginia Tech | 2.5 | 6 | |
| 9 PM | ESPN+ | UTEP | #24 Florida Atlantic | -5.5 | -7 | |
| 10 PM | Pacific | #6 Gonzaga | -16.5 | -17 | ||
| 9 PM | ESPN+ | Montana | Montana State | 1.5 | -1 | |
| 12 PM | ACCNX | Georgia Tech | Syracuse | -2.5 | -3 | |
| 1 PM | SECN | Georgia | Vanderbilt | 2.5 | 7 | Georgia -2.5 |
| 2 PM | ACCNX | Notre Dame | Boston College | 4.5 | 3 | |
| 2 PM | FOX | Ohio State | Iowa | 2.5 | 1 | |
| 2 PM | ESPN | Kentucky | Texas A&M | 4.5 | 0 | Texas A&M +4.5 |
| 2:15 PM | BTN | Penn State | Nebraska | 8.5 | 7 | |
| 3 PM | ACCN | Pittsburgh | Florida State | 7.5 | 15 | Pittsburgh -7.5 |
| 4 PM | FS1 | Wyoming | Colorado State | -1.5 | -4 | |
| 5 PM | ACCN | North Carolina | NC State | 6.5 | 3 | |
| 6 PM | CBSSN | Fresno State | UNLV | -3.5 | -6 | |
| 6 PM | Utah State | San Jose State | 11.5 | 10 | ||
| 8 PM | PAC12 | Utah | Washington | 8.5 | 6 | |
| 8:30 PM | SECN | Mississippi State | Florida | 2.5 | 5 | |
| 10 PM | ESPNU | Arizona State | USC | 4.5 | 6 | |
| 10 PM | CBSSN | Air Force | San Diego State | -8.5 | -8 | |
| 11 PM | FS1 | Stanford | Oregon | -3.5 | -7 |