#ppiupsetrecord: 24-38 (38.7%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6 PM | ESPN2 | #18 Tennessee | Florida | 10 | 7 | |
| 6:30 PM | CBSSN | #21 Xavier | #17 Providence | 8.5 | 4 | #ppiupsetalert, Providence +8.5 |
| 6:30 PM | FS1 | Butler | Creighton | -4.5 | -2 | |
| 6:30 PM | BTN | Michigan | Northwestern | 8 | 10 | |
| 7 PM | ACCN | Virginia Tech | Miami (FL) | 5 | -3 | Miami (FL) +180 |
| 7 PM | ACCNX | North Carolina | Boston College | 14 | 14 | |
| 7 PM | ESPNU | South Carolina | Vanderbilt | 2 | 4 | |
| 7 PM | SECN | Ole Miss | Arkansas | -4.5 | -3 | |
| 8 PM | ESPN+ | Oklahoma State | #23 Iowa State | 3.5 | 2 | #ppiupsetalert |
| 8 PM | ESPN2 | West Virginia | Oklahoma | 2 | 4 | |
| 8:30 PM | FS1 | Seton Hall | Marquette | 5 | -2 | Marquette +184 |
| 8:30 PM | CBSSN | #25 Davidson | VCU | 4 | 11 | Davidson -4 |
| 8:30 PM | BTN | Indiana | Penn State | 8.5 | 8 | |
| 9 PM | SECN | #19 LSU | Texas A&M | 8.5 | 9 | |
| 9 PM | ESPN+ | Notre Dame | NC State | 5 | 5 | |
| 9 PM | ACCN | Georgia Tech | Florida State | -5.5 | -7 | |
| 10 PM | PAC12 | Washington State | Utah | 7 | 11 | Washington State -7 |
| 10:30 PM | FS1 | Utah State | San Diego State | -2 | -2 |