#ppiupsetalert record: 17-24 (.415)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6 PM | ACCN | #16 Florida State | Miami (FL) | 11 | 16 | Florida State -11 |
| 7 PM | BTN | #13 Ohio State | Penn State | 8 | 14 | Ohio State -8 |
| 7 PM | FS1 | Seton Hall | #17 Creighton | -1.5 | 2 | Seton Hall +105 |
| 7 PM | ACCNX | Notre Dame | #20 Virginia Tech | 0 | -2 | #ppiupsetalert, Notre Dame pick |
| 8 PM | Maryland | #14 Wisconsin | -3 | -1 | #ppiupsetalert, Maryland +3 | |
| 9 PM | ESPN2 | #2 Baylor | Kansas State | 24 | 28 | Baylor -24 |
| 9 PM | ACCNX | Clemson | #25 Louisville | 1.5 | 4 | |
| 6:30 PM | SECN | Florida | Vanderbilt | 12.5 | 14 | |
| 7 PM | CBSSN | Providence | Marquette | 1.5 | 6 | Providence -1.5 |
| 7 PM | ESPN2 | South Carolina | Georgia | 4.5 | 1 | Georgia +4.5 |
| 8 PM | ACCN | NC State | Wake Forest | 7.5 | 6 | |
| 8:30 PM | SECN | Arkansas | Ole Miss | 4.5 | 10 | Arkansas -4.5 |
| 9 PM | FS1 | DePaul | St. John’s | 0 | -3 | St. John’s pick |
| 9 PM | ESPNU | Colorado | Washington State | 14.5 | 13 |