#ppiupsetalertrecord 19-16 (54.3%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12 PM | FS1 | #15 Indiana | Northwestern | 6.5 | -3 | #ppiupsetalert, Northwestern +225 |
| 1 PM | ESPN | Maryland | #24 Ohio State | 1.5 | 6 | #ppiupsetalert, Maryland -114 |
| 3 PM | ESPN | Cincinnati | #2 Houston | -9.5 | -7 | |
| 6 PM | BTN | Penn State | #1 Purdue | -5.5 | -5 | #ppiupsetalert, Penn State +5.5 |
| 12 PM | BTN | Rutgers | Iowa | 5.5 | 7 | |
| 5 PM | ESPN | Arizona State | Washington | 9.5 | 9 |