#tourneyspreadrecord 6-8 (42.9%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12:10 PM | CBS | #4 Illinois | #5 Houston | -3.5 | -1 | South Round 2 |
| 2:40 PM | CBS | #2 Villanova | #7 Ohio State | 5 | 13 | South Round 2 – Villanova -5 |
| 5:15 PM | CBS | #2 Duke | #7 Michigan State | 6.5 | 11 | West Round 2 – Duke -6.5 |
| 6:10 PM | TNT | #3 Wisconsin | #11 Iowa State | 4.5 | 9 | Midwest Round 2 – Wisconsin -4.5 |
| 7:10 PM | TBS | #3 Texas Tech | #11 Notre Dame | 8 | 8 | West Round 2 |
| 7:45 PM | TRUTV | #2 Auburn | #10 Miami (FL) | 7.5 | 9 | Midwest Round 2 |
| 8:40 PM | TNT | #3 Purdue | #6 Texas | 3.5 | 11 | East Round 2 – Purdue -3.5 |
| 9:40 PM | TBS | #1 Arizona | #9 TCU | 9.5 | 16 | South Round 2 – Arizona -9.5 |