| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12:15 PM | CBS | #25 Mississippi State | Baylor | 1.5 | 3 | East Rd 1 (Raleigh) |
| 12:40 PM | TruTV | #7 Alabama | Robert Morris | 21.5 | 12 | East Rd 1 (Cleveland), Robert Morris +22.5 |
| 1:30 PM | TNT | #10 Iowa State | Lipscomb | 14.5 | 5 | South Rd 1 (Milwaukee), Lipscomb +14.5 |
| 2 PM | TBS | #16 Memphis | Colorado State | -1.5 | 0 | West Rd 1 (Seattle) |
| 2:50 PM | CBS | #2 Duke | Mount St. Mary’s | 32.5 | 18 | East Rd 1 (Raleigh), Mount St. Mary’s +32.5 |
| 3:15 PM | TruTV | #21 Saint Mary’s | Vanderbilt | 4.5 | 6 | East Rd 1 (Cleveland) |
| 4:05 PM | TNT | Ole Miss | North Carolina | -1.5 | -1 | South Rd 1 (Milwaukee) |
| 4:35 PM | TBS | #13 Maryland | Grand Canyon | 10.5 | 7 | West Rd 1 (Seattle), Grand Canyon +10.5 |
| 6:50 PM | TNT | #5 Florida | Norfolk State | 28.5 | 20 | West Rd 1 (Raleigh), Norfolk St +28.5 |
| 7:10 PM | CBS | #19 Kentucky | Troy | 11.5 | 6 | Midwest Rd 1 (Milwaukee), Troy +11.5 |
| 7:25 PM | TBS | #20 Marquette | New Mexico | 3.5 | 1 | South Rd 1 (Cleveland), New Mexico +3.5 |
| 7:35 PM | TruTV | #24 Arizona | Akron | 14.5 | 7 | East Rd 1 (Seattle), Akron +14.5 |
| 9:25 PM | TNT | Connecticut | Oklahoma | 5.5 | 4 | West Rd 1 (Raleigh) |
| 9:45 PM | CBS | Illinois | Xavier | 3.5 | . | Midwest Rd 1 (Milwaukee) |
| 10 PM | TBS | #8 Michigan State | Bryant University | 16.5 | 20 | South Rd 1 (Cleveland), Michigan St -16.5 |
| 10:10 PM | TruTV | Oregon | Liberty | 6.5 | 3 | East Rd 1 (Seattle), Liberty +6.5 |
PPI Projections: March 21, 2025
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