| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 7:09 PM | CBS | #7 Alabama | #23 BYU | 5.5 | 5 | East S16 (Newark) |
| 7:39 PM | TBS/TruTV | #5 Florida | #13 Maryland | 6.5 | 7 | West S16 (San Francisco) |
| 9:39 PM | CBS | #2 Duke | #24 Arizona | 9.5 | 7 | East S16 (Newark) |
| 10:09 PM | TBS/TruTV | #9 Texas Tech | Arkansas | 5.5 | 3 | West S16 (San Francisco) |
PPI Projections: March 27, 2025
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