#ppiupsetalertrecord: 55-65 (45.8%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12:30 PM | ESPN+ | Louisiana Lafayette | UT-Arlington | 3.5 | 0 | Sun Belt Round 1 (N) |
| 3 PM | ESPN+ | South Alabama | Arkansas-Little Rock | 13 | 10 | Sun Belt Round 1 (N) |
| 6 PM | ESPN+ | Arkansas State | Louisiana Monroe | 6.5 | 7 | Sun Belt Round 1 (N) |
| 7 PM | ESPN2 | #14 Houston | Temple | 15 | 14 | |
| 7 PM | FS1 | #20 Illinois | Penn State | 12.5 | 14 | |
| 7 PM | ESPN | #23 Ohio State | Michigan State | 6 | 2 | #ppiupsetalert, Michigan State +6 |
| 7 PM | ESPN+ | Fort Wayne | UIC | 6.5 | 11 | Horizon Round 1: Fort Wayne -6.5 |
| 7 PM | ESPN+ | Northern Kentucky | Detroit Mercy | 3.5 | 5 | Horizon Round 1 |
| 7 PM | ESPN+ | Wright State | Oakland | 3.5 | 1 | Horizon Round 1 |
| 7 PM | ESPN+ | Colgate | Bucknell | 15.5 | 19 | Patriot Round 1 |
| 7 PM | ESPN+ | Navy | American University | 11.5 | 15 | Patriot Round 1: Navy -11.5 |
| 7 PM | ESPN+ | Boston University | Loyola (MD) | 5.5 | 9 | Patriot Round 1: Boston U. -5.5 |
| 7 PM | ESPN+ | Lehigh | Army | 1.5 | 3 | Patriot Round 1 |
| 7 PM | ESPN+ | Illinois State | Indiana State | 1.5 | 1 | Patriot Round 1 |
| 7 PM | ESPN+ | Jacksonville | Central Arkansas | 9.5 | 12 | Atlantic Sun QFs |
| 7 PM | ESPN+ | Jacksonville State | Kennesaw State | 7.5 | 12 | Atlantic Sun QFs: Jacksonville St. -7.5 |
| 7 PM | ESPN+ | Bellarmine | Florida Gulf Coast | 2.5 | 2 | Atlantic Sun QFs |
| 7 PM | ESPN+ | Liberty | Lipscomb | 10.5 | 12 | Atlantic Sun QFs |
| 7:30 PM | ESPN+ | Southeast Missouri State | Tennessee State | 2.5 | 0 | OVC QFs (N) |
| 8 PM | ESPN+ | #6 Kansas | TCU | 12 | 10 | |
| 8 PM | ESPN+ | Cleveland State | Robert Morris | 11.5 | 11 | OVC QFs (N) |
| 8 PM | Arizona State | California | 7.5 | 9 | ||
| 8:30 PM | ESPN+ | Coastal Carolina | Georgia Southern | 5.5 | 4 | Sun Belt Round 1 (N) |
| 9 PM | ESPN+ | Montana State | Sacramento State | 12.5 | 16 | Montana State -12.5 |
| 9 PM | ESPN2 | #2 Arizona | Stanford | 18.5 | 20 | |
| 9 PM | FS1 | Michigan | #24 Iowa | 2 | 3 | #ppiupsetalert, Michigan -132 |
| 9 PM | Loyola Marymount | Pacific | 5.5 | 5 | West Coast Round 1 (N) | |
| 9:30 PM | ESPN+ | Valparaiso | Evansville | 5.5 | 7 | MVC Tourney Round 1 (N) |
| 10 PM | ESPN+ | Morehead State | Tennessee Tech | 7.5 | 8 | OVC QFs (N) |
| 10 PM | Washington | Oregon | -5 | 0 | Washington +172 | |
| 11 PM | CBSSN | San Diego State | Fresno State | 7.5 | 10 | |
| 11 PM | San Diego | Pepperdine | 5.5 | 7 | West Coast Round 1 (N) |