#ppiposseofpicks: 182-208 (.467)
#ppiupsetalert: 61-69 (.469)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | FOX | Georgetown | #14 Villanova | -7.5 | -6 | |
| 12 PM | ESPN2 | Tennessee | #17 Auburn | 2.5 | 0 | #ppiupsetalert, #closegamealert, Tennessee -148, #TennesseeBubble |
| 12 PM | ESPN | Indiana | #24 Wisconsin | 2 | 1 | #ppiupsetalert, Indiana-136, #IndianaBubble |
| 12 PM | St. John’s | Marquette | -1 | -1 | #MarquetteBubble | |
| 12:30 PM | SECN | Vanderbilt | South Carolina | -4.5 | -4 | |
| 1 PM | ESPN+ | West Virginia | #4 Baylor | 1 | -3 | #ppiupsetalert, WVU -115 |
| 1 PM | CBS | Florida | #6 Kentucky | 3 | -1 | #ppiupsetalert, Florida -159, #FloridaBubble |
| 2 PM | ESPN | Texas Tech | #1 Kansas | -3.5 | -9 | Kansas -3.5, #TexasTechBubble |
| 2 PM | ACCN | Notre Dame | Virginia Tech | 7 | 8 | #NotreDameBubble |
| 2 PM | ESPN2 | LSU | Georgia | 9 | 10 | #LSUBubble |
| 2 PM | BTN | Purdue | Rutgers | 6 | 6 | #PurdueBubble |
| 2:30 PM | FOX | #11 Creighton | #8 Seton Hall | 3.5 | 3 | #ppiupsetalert, Creighton -155 |
| 2:30 PM | PAC12 | Utah | Colorado | -3 | -5 | |
| 2:30 PM | SECN | Missouri | Alabama | 1 | 0 | #closegamealert, #AlabamaBubble |
| 3:15 PM | CBS | USC | UCLA | 4 | 5 | #UCLABubble |
| 4 PM | ESPN | #22 Virginia | #10 Louisville | 1 | 1 | #ppiupsetalert, UVA -117 |
| 4 PM | BTN | Northwestern | Penn State | -7.5 | -10 | |
| 4 PM | ACCN | Miami (FL) | Syracuse | -1 | 0 | #closegamealert, #SyracuseBubble |
| 4 PM | ESPN2 | Texas | Oklahoma State | 3.5 | 6 | #TexasBubble |
| 4 PM | ESPN+ | Kansas State | Iowa State | 5.5 | -1 | Iowa State +170 |
| 4:30 PM | ACCNX | #7 Florida State | Boston College | 16.5 | 18 | |
| 4:30 PM | SECN | Texas A&M | Arkansas | -3.5 | 0 | #closegamealert, Texas A&M +135 |
| 4:30 PM | PAC12 | Oregon State | California | 9 | 5 | |
| 5:30 PM | CBS | #5 San Diego State (N) | Utah State (N) | 13 | MWC Finals | |
| 6 PM | ESPN | #12 Duke | North Carolina | 11.5 | 15 | |
| 6 PM | ESPN+ | Furman (N) | TBD (N) | 9 | Southern Quarterfinals, #FurmanBubble | |
| 6 PM | Montana State | Northern Colorado | -5.5 | -2 | ||
| 6 PM | ESPN2 | TCU | Oklahoma | 1 | 0 | #closegamealert, #OklahomaBubble |
| 6:30 PM | FS1 | Providence | DePaul | 10 | 10 | |
| 6:30 PM | SECN | Mississippi State | Ole Miss | 6 | 9 | #MissStBubble |
| 6:30 PM | PAC12 | Arizona State | Washington State | 10 | 11 | #ArizonaStateBubble |
| 7 PM | ESPN+ | #3 Dayton | George Washington | 22 | 25 | |
| 7 PM | ESPN3 | South Florida | SMU | 0 | 1 | |
| 7 PM | ESPN+ | Massachusetts | Rhode Island | -2.5 | -2 | #RhodeIslandBubble |
| 8 PM | Saint Louis | St. Bonaventure | 5.5 | 9 | #SaintLouisBubble | |
| 8 PM | CBSSN | Cincinnati | Temple | 10.5 | 12 | |
| 8:30 PM | FS1 | Xavier | Butler | 2.5 | 2 | |
| 10 PM | ESPN | Arizona | Washington | 10.5 | 11 | |
| 11 PM | FS1 | #13 Oregon | Stanford | 7.5 | 8 | #StanfordBubble |
| 11:59 PM | ESPN2 | Saint Mary’s (N) | Pepperdine (N) | 9 | West Coast Quarterfinals |