#ppiupsetalertrecord: 0-0 (0.0%)
| Time | Chan | Home | Away | Spread | Expected |
| 7 PM | ESPN2 | #25 Ohio State | Rutgers | 6 | 6 |
| 8 PM | FS1 | Iowa | #20 Iowa State | 5 | 5 |
| 9 PM | BTN | Minnesota | Michigan | -4.5 | -1 |
| 9 PM | ESPN2 | Colorado | Colorado State | 5.5 | 5 |
| 10 PM | PAC12 | Utah | Jacksonville State | 14.5 | 12 |
#ppiupsetalertrecord: 0-0 (0.0%)
| Time | Chan | Home | Away | Spread | Expected |
| 7 PM | #4 Purdue | Hofstra | 22.5 | 17 | |
| 7 PM | SECN | #7 Tennessee | Eastern Kentucky | 29.5 | 22 |
| 8:30 PM | BTN | #14 Indiana | Nebraska | 13.5 | 6 |
| 9 PM | ESPN2 | Florida | #5 Connecticut | -4.5 | -13 |
| 6:30 PM | FS1 | St. John’s | DePaul | 8.5 | 6 |
| 6:30 PM | FS2 | Georgetown | Siena | 6 | -2 |
| 6:30 PM | BTN | Penn State | Michigan State | 3.5 | 7 |
| 7 PM | CBSSN | Villanova | Pennsylvania | 14.5 | 4 |
| 7 PM | ESPNU/+ | West Virginia | Navy | 18 | 17 |
| 7 PM | ESPN+/ACCNX | Notre Dame | Boston University | 14 | 14 |
| 7 PM | ACCNX | Miami (FL) | Cornell | 15 | 14 |
| 8 PM | ESPN+ | Texas Tech | Nicholls State | 22.5 | 14 |
| 8 PM | ACCN | Virginia Tech | Dayton | 7 | 11 |
| 8:30 PM | FS1 | Providence | Manhattan | 19.5 | 13 |
| 9 PM | Washington State | Northern Kentucky | 12.5 | 9 | |
| 9 PM | ESPNU | SMU | Arizona State | -5.5 | -17 |
| 9 PM | SECN | Vanderbilt | Pittsburgh | 3.5 | 2 |
| 9 PM | ACCNX | Clemson | Towson | 7 | 5 |
| 10 PM | California | Eastern Washington | 3.5 | -5 | |
| 11 PM | PAC12 | USC | Cal State Fullerton | 14 | 14 |
#tourneyspreadrecord 15-13 (53.6%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 9:20 PM | TBS | #1 Kansas | #8 North Carolina | 4 | 9 | National Championship – Kansas -4 |
#tourneyspreadrecord 15-12 (55.6%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:09 PM | TBS | #1 Kansas | #2 Villanova | 4 | 6 | Final Four |
| 8:49 PM | TBS | #2 Duke | #8 North Carolina | 4 | 8 | Final Four – Duke -4 |
#tourneyspreadrecord 13-12 (52.0%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 2:20 PM | CBS | #1 Kansas | #10 Miami (FL) | 5.5 | 11 | Midwest Elite 8 – Kansas -5.5 |
| 5:05 PM | CBS | #8 North Carolina | #15 Saint Peter’s | 8.5 | 16 | East Elite 8 – North Carolina -8.5 |
#tourneyspreadrecord 12-12 (50.0%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:09 PM | TBS | #5 Houston | #2 Villanova | 3 | 5 | South Elite 8 |
| 8:49 PM | TBS | #2 Duke | #4 Arkansas | 4 | 10 | West Elite 8 – Duke -4 |
#tourneyspreadrecord 11-11 (50.0%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7:09 PM | CBS | #3 Purdue | #15 Saint Peter’s | 13 | 18 | East Sweet 16 – Purdue -13 |
| 7:29 PM | TBS | #1 Kansas | #4 Providence | 7 | 10 | Midwest Sweet 16 |
| 9:39 PM | CBS | #4 UCLA | #8 North Carolina | 2.5 | 6 | East Sweet 16 |
| 9:59 PM | TBS | #10 Miami (FL) | #11 Iowa State | 3 | 8 | Midwest Sweet 16 – Miami (FL) -3 |
#tourneyspreadrecord 9-10 (47.4%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7:09 PM | CBS | #1 Gonzaga | #4 Arkansas | 10 | 8 | West Sweet 16 |
| 7:29 PM | TBS | #2 Villanova | #11 Michigan | 5 | 11 | South Sweet 16 – Villanova -5 |
| 9:39 PM | CBS | #2 Duke | #3 Texas Tech | -1 | 9 | West Sweet 16 – Duke -108 |
| 9:59 PM | TBS | #1 Arizona | #4 Houston | 1.5 | 7 | South Sweet 16 – Arizona -1.5 |
#tourneyspreadrecord 6-8 (42.9%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12:10 PM | CBS | #4 Illinois | #5 Houston | -3.5 | -1 | South Round 2 |
| 2:40 PM | CBS | #2 Villanova | #7 Ohio State | 5 | 13 | South Round 2 – Villanova -5 |
| 5:15 PM | CBS | #2 Duke | #7 Michigan State | 6.5 | 11 | West Round 2 – Duke -6.5 |
| 6:10 PM | TNT | #3 Wisconsin | #11 Iowa State | 4.5 | 9 | Midwest Round 2 – Wisconsin -4.5 |
| 7:10 PM | TBS | #3 Texas Tech | #11 Notre Dame | 8 | 8 | West Round 2 |
| 7:45 PM | TRUTV | #2 Auburn | #10 Miami (FL) | 7.5 | 9 | Midwest Round 2 |
| 8:40 PM | TNT | #3 Purdue | #6 Texas | 3.5 | 11 | East Round 2 – Purdue -3.5 |
| 9:40 PM | TBS | #1 Arizona | #9 TCU | 9.5 | 16 | South Round 2 – Arizona -9.5 |
#tourneyspreadrecord 6-7 (46.2%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12:10 PM | CBS | #1 Baylor | #8 North Carolina | 5.5 | 6 | East Round 2 |
| 2:40 PM | CBS | #1 Kansas | #9 Creighton | 12.5 | 12 | Midwest Round 2 |
| 5:15 PM | CBS | #3 Tennessee | #11 Michigan | 6.5 | 12 | South Round 2 – Tennessee -6.5 |
| 6:10 PM | TNT | #4 Providence | #12 Richmond | 3.5 | 6 | Midwest Round 2 |
| 7:10 PM | TBS | #4 UCLA | #5 Saint Mary’s | 3 | 6 | East Round 2 |
| 7:45 PM | CBS | #7 Murray State | #15 Saint Peter’s | 9 | 9 | East Round 2 |
| 8:40 PM | TNT | #4 Arkansas | #12 New Mexico State | 7 | 8 | West Round 2 |
| 9:40 PM | TBS | #1 Gonzaga | #9 Memphis | 9.5 | 9 | West Round 2 |