#ppiposseofpicks: 58-74 (.439)
#ppiupsetalert: 10-10 (.500)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | FS1 | #11 Butler | Creighton | 5.5 | 12 | #ppiposseofpicks: Butler -5.5 |
| 12 PM | FOX | #15 Maryland | Indiana | 7 | 8 | |
| 12 PM | ESPN2 | #22 Texas Tech | Oklahoma State | 5.5 | -1 | #ppiupsetalert, #ppiposseofpicks: Okla St +180 |
| 1 PM | CBS | #9 Memphis | Georgia | 8 | 11 | |
| 2 PM | ESPN2 | #7 Louisville | #18 Florida State | 6.5 | 2 | #ppiupsetalert, #ppiposseofpicks: Florida St +210 |
| 2 PM | FOX | Marquette | #10 Villanova | 1 | 2 | |
| 2 PM | SECN | #17 Kentucky | Missouri | 8 | 4 | |
| 2 PM | ACCNX | #19 Virginia | Virginia Tech | 7.5 | 8 | |
| 2 PM | BTN | #21 Penn State | #23 Iowa | 2.5 | 5 | #ppipupsetalert, #ppiposseofpicks: Iowa +2.5 |
| 4 PM | ESPN+ | #3 Kansas | #18 West Virginia | 10 | 2 | #ppiupsetalert, #ppiposseofpicks: West Virginia +450 |
| 4 PM | ESPNU | #24 Wichita State | Ole Miss | 8 | 12 | |
| 4:30 PM | SECN | Mississippi State | #8 Auburn | -1.5 | -2 | #ppiupsetalert, #ppiposseofpicks: Miss St +105 |
| 5 PM | PAC12 | Utah | #4 Oregon | -5 | -3 | #ppiupsetalert, #ppiposseofpicks: Utah +180 |
| 8 PM | ESPN | Miami (FL) | #2 Duke | -9.5 | -4 | #ppiupsetalert, #ppiposseofpicks: Miami (FL) |
| 8 PM | ESPN2 | #6 Baylor | Texas | 8.5 | 7 | |
| 9:30 PM | PAC12 | #25 Arizona | Arizona State | 11 | 5 | |
| 10 PM | ESPN2 | #1 Gonzaga | Pepperdine | 21 | 28 | #ppiposseofpicks: Gonzaga -21 |
| 10 PM | CBSSN | Utah State | #13 San Diego State | 2.5 | -5 | #ppiposseofpicks: San Diego St +125 |
| 12 PM | ACCNX | Pittsburgh | Wake Forest | 6.5 | 8 | |
| 12 PM | ACCN | Clemson | NC State | -2 | -5 | |
| 4 PM | ESPN2 | Syracuse | Notre Dame | 3 | 5 | |
| 6 PM | ACCN | North Carolina | Georgia Tech | 8 | 8 | |
| 2 PM | ESPNU | South Florida | Connecticut | -3.5 | 1 | #ppiposseofpicks: South Florida +155 |
| 4 PM | CBSSN | Tulane | Cincinnati | -7.5 | -1 | #ppiposseofpicks: Tulane +270 |
| 9 PM | SECN | Vanderbilt | SMU | -2 | -3 | |
| 1 PM | ESPN+ | Oklahoma | Kansas State | 7 | 12 | #ppiposseofpicks: Oklahoma -7 |
| 6 PM | ESPNU | TCU | Iowa State | 4 | 7 | |
| 2 PM | FS1 | DePaul | Providence | 2.5 | 13 | #ppiposseofpicks: DePaul -2.5 |
| 4 PM | Southern Utah | Montana State | 7.5 | 6 | ||
| 7 PM | PAC12 | Washington State | UCLA | 1 | 4 | |
| 12 PM | ESPNU | Tennessee | LSU | -1 | 2 | #ppiposseofpicks: Tennessee +1 |
| 6 PM | ESPN2 | Florida | Alabama | 6.5 | 3 | |
| 7 PM | SECN | Arkansas | Texas A&M | 14 | 18 |