#ppiupsetalertrecord: 76-84 (.475)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 7:09 PM | CBS | #2 Arizona | #6 Clemson | 7.5 | 7 | West S16 (Los Angeles) |
| 7:39 PM | TBS | #1 Connecticut | #5 San Diego State | 11.5 | 8 | East S16 (Boston), San Diego St +11.5 |
| 9:39 PM | CBS | #1 North Carolina | #4 Alabama | 4.5 | 8 | West S16 (Los Angeles), North Carolina -4.5 |
| 10:09 PM | TBS | #2 Iowa State | #3 Illinois | 1.5 | 1 | East S16 (Boston) |